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It was awful. A tragic mistake GLP-1 drugs like semaglutide (Ozempic and Wegovy) and tirzepatide (Zepbound and Mounjaro) have changed obesity treatment for the better, allowing people to lose significantly more weight on average than they would with diet and exercise alone

The emergence of a metabolic drug that incidentally reduces addictive behavior underscores something many clinicians have long suspected: addiction is deeply intertwined with the bodys fundamental regulatory systems appetite, satiety, stress, reward, inflammation including behaviors like binge eating that share overlapping neural pathways