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Additional information Journal peer review information : Nature Communications thanks the anonymous reviewers for their contribution to the peer review of this work

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One rat study exists showing that sodium glycocholate liposomes can improve semaglutide absorption via intestinal bile acid transporters

In the present study, by focusing on intestinal L-cells and pancreatic -cells, we discovered the commonalities and differences between insulin and GLP-1 secretions, using GLUTag cells and MIN-6 cells