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Overexpression of human hepsin in adult mice with AAV administration For the APAP susceptibility test, mice were made to overexpress human hepsin in the liver through transduction with 2.5 10 10 viral genome (vg) per mouse of AAV-hHPN WT /hHPN RS /EGFP via retro-orbital injection
Modele wrzodw odka indukowanych etanolem lub NLPZ, modele zapalenia jelita grubego (kwas octowy, TNBS)
Co-treatment with Erastin showed severe muscle fiber disruption, significantly increased fibrosis, and extensive collagen deposition
References Akter N, Sobahan MA, Uraji M, Ye W, Hossain MA, Mori IC, Nakamura Y, Murata Y
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