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Another key role of B12, along with folic acid, is helping to turn homocysteine into methionine

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This can cause: Tremors Hallucinations (delirium tremens) Seizures Increased heart rate and blood pressure Withdrawal can begin as early as 624 hours after the last drink and may become life-threatening without proper management

The only meaningful comparison context is against the other agents in the class, covered in our Retatrutide vs Semaglutide vs Tirzepatide analysis, and the two entry points for the protocol itself are the 5 mg vial protocol for a gentle start and the 30 mg vial protocol for higher maintenance targets