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A phase 1 open-label, accelerated dose-escalation study of the hypoxia-activated prodrug AQ4N in patients with advanced Malignancies

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A higher amount of Hcy in follicular fluid of PCOS women undergoing oocyte pick-up following FSH stimulation sharply marked lower oocyte quality, fertilization rates, embryo quality, and pregnancy rates with no pregnancies occurring from oocytes whose follicles contained more than 8 molar Hcy [9]

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