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Experimental results showed that metformin effectively lowered total testosterone levels and free androgen index ( Metformin exerts its efficacy by effectively reducing blood glucose levels, mitigating IR, and facilitating improvements in abnormal glucose metabolism markers

This ongoing oxidative stress leaves endothelial cells (the lining of blood vessels) highly vulnerable to ongoing damage, contributing to the micro-clotting and "immunothrombosis" frequently observed in Long Haulers

However, reduced sebum production can leave the skin dry

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