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Given that MTX is more effective against dividing cells because of its effect on the nucleotide synthesis, we also examined correlations between metabolites concentrations and cell proliferation rate, as this could be a confounding factor (proliferation curves for doubling time determination are in Supplemental Figure 5 )

Although available in wellness settings, AOD-9604 is not FDA-approved and should be used strictly in research contexts

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Contrastingly, hair regrowth was only observed in 13% of the control group, making the findings of this study statistically significant