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A higher-dose semaglutide tablet (25 mg) led to an average weight loss of about 1417% over a little more than a year , along with additional benefits like lower blood pressure and reduced inflammation

This is because after this period, the bacteriostatic preservative can no longer prevent contamination, often leading to a compromised product that can put the patients at risk

Because retatrutide has not yet received MHRA or EMA approval, it is not currently available through NHS prescriptions or licensed private clinics in the UK

The US and Europe, but not the UK, recommend higher levels for pregnant and breastfeeding women