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Historical Context The roots of the opioid epidemic can be traced back to the late 1990s when pharmaceutical companies reassured the medical community that patients would not become addicted to prescription opioid pain relievers

You may qualify for GLP-1 weight loss treatment with semaglutide or tirzepatide if your weight is affecting your health, mobility, confidence, or quality of life

Like them, you may also be asking the question, why am I not losing weight on semaglutide? Your progress could be hindered by one or more of several key factors

Visual indicators of compromised medication: Particles or cloudiness : Any visible particles, cloudiness, or haziness indicates potential problems Color change : Darkening, browning, or any discoloration suggests chemical degradation Crystallization : Visible crystals or precipitate formation Separation : Layering or separation of solution components Damaged pen : Cracks, leaks, or mechanical malfunction of the injection device Beyond visual inspection, patients should consider the medication's storage history