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351,352,353 Diabetic macroangiopathy and neuropathy are also important risk factors for DKD

ASK1, apoptosis signal-regulating kinase 1

Brian Finan, then at the Helmholtz Institute for Diabetes and Obesity Research and the Indiana University laboratory of Richard DiMarchi, published a paper in Science Translational Medicine describing the first unimolecular dual incretin agonist: a single peptide that activated both GLP-1R and GIPR with balanced potency