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A week-long vacation with daily happy hours can seriously derail your progress if you approach it without a plan

doi:10.1016/j.neuropharm.2008.06.013 Pakseresht S, Boostani H, Sayyah M

Vitamin B12 injections work by being released into the bloodstream

While it remains to be established if specifically inhibiting LC-NE neurons has a similar effect, these findings suggest that systemic GLP-1R agonists activate presynaptic GLP-1Rs on glutamatergic terminals synapsing onto LC-NE neurons, leading to their activation and suppression of food intake