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Furthermore, emerging strategies, such as acetazolamide combined with remote ischemic preconditioning (RIPC), have shown additional risk reductions under controlled hypoxia exposure

Importantly, the strength of interaction between CPP and cargo positively correlates with the delivery efficiency across the nasal mucosa of rats (Khafagy et al., 2010b)

No controlled study has tested the two in combination against either alone, so combination-specific claims cannot be supported

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