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However, treatment of HL-60 cells with a nitrile inhibitor that reduces both DPP1 and NSP-AAP activities by approximately 95% results in near-complete NSP inactivation ( Granzymes are serine proteases with various substrate specificities that are expressed almost exclusively in cytotoxic T cells and natural killer cells

CAR-T cells technology is an ex vivo method, which genetically modifies patient derived cells for immunotherapeutic purposes

The HRP reaction was terminated by addition of 1 M HCl and the 450 nM (HRP) or 405 nm (AP) absorption values was recorded using a Sunrise Spectrophotometer (TECAN)

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