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Chitosan nanoparticles with positive charge can bind to fungal cell walls and cell membranes with negative charge, which will lead to increased permeability of cell envelopes and leakage of cytoplasmic contents from the cells, including ions and protein [66]

Acute gallbladder disease: Pain in the middle or upper right stomach, fever, yellowing of the skin or eyes (jaundice), nausea or vomiting