semaglutide mash fda approval Novo's Wegovy becomes first GLP-1 drug approved for FDA Approves Semaglutide for MASH

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AA: Project administration, Formal Analysis, Resources, Data curation, Writing original draft, Methodology, Visualization, Conceptualization, Supervision, Investigation, Validation, Software, Funding acquisition, Writing review and editing

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492 Interestingly, CP26, a small molecule inhibitor of substrate translocation from the ER to the cytoplasm during ERAD, targets the SEL1L-HRD1 complex and attenuates SEL1L-HRD1 ERAD, thereby inducing ER stress, which results in substantial protection of host cells against virus-induced cell death