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Symptoms range from persistent fatigue, brain fog, and shortness of breath to more severe complications such as cardiovascular issues and multisystem inflammatory syndromes
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Moreover, baseline BCAA catabolic capacitywhich varies with BCKDH genetic polymorphisms (131), gut microbiota composition (132), and adipose tissue metabolic status (33)is rarely characterized, precluding the identification of metabolic responders and non-responders
Although the calorimetry did not demonstrate a significant increase in lipid oxidation, the expression of proteins related to fatty acid oxidation such as PPAR and CPT-1 was significantly increased by Godex, and it is likely that glucose oxidation was more increased as a result of CrAT activation
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