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It exhibits significant polymorphism, to date at least 100 allelic variants of A1AT have been described

11.5 Pharmacokinetics and bioavailability It is evident that following oral administration, resveratrol is rapidly absorbed in the gastrointestinal tract (75%) with an extensive first-pass metabolism in the intestine and liver, lowering its oral bioavailability (ranging from 2.6 to 75% in humans and 2029% in rats fed 50 mg/kg) [198]

Ursini F, Heim S, Kiess M, Maiorino M, Roveri A, Wissing J, Floh L

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