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Prospective studies should identify the mechanisms underlying the efficacy of L-carnitine/N-acetylcysteine and evaluate the safety and effectiveness of combination antioxidant treatments against male infertility

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In fact, supplementation of glycine for 4 weeks resulted in an 85% increase in aortic GSH, 64% decrease in aortic GSSG, and an overall significantly higher GSH/GSSG ratio [53], with a concomitant increase in expression levels of GSH biosynthetic enzymes