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Sterile compounds are manufactured in a so-called "clean room" where a monitoring system constantly measures pressure, temperature, humidity and particulate levels

Here, we used chemoproteomics to investigate the protein alkylation targets of artemisinin and ozonide probes, including an analogue of the ozonide clinical candidate, artefenomel

In mammalian cells, ER stress leads to an integrated stress response involving the related transmembrane kinases Ire1, Ire1 and PKRlike ER kinase (PERK), and the transmembrane activating transcription factor 6 (ATF6) (Zhang & Kaufman, 2004)

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