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Some biological effects shown by betanin are reduced in two redox-sensitive pathways, nuclear factor kappa B (NFkB) and nuclear factor erythroid-2-related factor (Nrf2)antioxidant response element (ARE) are the major transcription genes for inflammatory responses, and are detoxifying/antioxidant (184, 185)

Whilst it has a paracrine or endocrine role in the periphery, centrally GLP-1 is an important neuroendocrine agent

Spatial transcriptomics in breast cancer reveals tumour microenvironment-driven drug responses and clonal therapeutic heterogeneity

[128] stated that acetyl-L-carnitine at a dose of 2050 mg/kg/day (for 12 months) decreased irritability and improved the social behavior of young boys with breakable X chromosomes, where ASD symptoms occurred in more than 60% cases