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Maybe even stopped

The blood samples were diluted 1:2 in phosphate-buffered saline (PBS), layered onto a separation solution (Biocoll 1.077 g/ml, Biochrom AG, Berlin, Germany), and centrifuged (800 x g, 20 min, 20C, Multifuge X3 F2, Thermo Fisher Scientific, Dreieich, Germany)

In addition, that extract increases the activity of antioxidant enzymes (CAT, SOD, and GPx) and increases reduced glutathione levels in the lens, mitigating oxidative stress and potentially preventing cataract formation [129]

Weight loss recommendations may be particularly important for patients at highest risk for weight gain and cardiovascular morbidity, such as young/premenopausal patients, postmenopausal patients with estrogen receptorpositive disease on endocrine therapy, and/or preexisting cardiovascular disease risk factors