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Therefore, to properly improve and establish the clinical beneficial effects of high doses of L-C in CAD patients, further long-term and large-scale intervention studies are needed

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This helps patients adjust to new eating habits and achieve steady, sustainable results

Specifically, prolonged inhibition of KGDHC in both neuroblastoma cells and primary neurons has been shown to enhance the calcium response to potassium-induced depolarization by approximately 2843% following 24 to 48 h of treatment (Gibson et al., 2012)