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In vivo imaging of islet vasculature [71,72,73] and islet function [69, 70, 74] have been performed successfully in anaesthetised animals, specifically, the mouse [69, 70, 72,73,74] and non-human primate [71]

Preclinical studies have clearly demonstrated that GLP-1RAs effectively reduce hepatic macrophage infiltration and suppress expression of TNF- , IL-6, and other pro-inflammatory mediators in animal models of MASLD (21, 22)

None of the patients had received preoperative chemotherapy or radiotherapy

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