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Ipamorelin avoids these issues

While semaglutide significantly impacts gastrointestinal functionprimarily by slowing gastric emptying and reducing appetitecurrent evidence does not support claims that it directly heals gut pathology

doi:10.2337/dc13-2760 31

Diabetic Retinopathy Complications Another serious side effect linked to GLP-1 drugs is worsening diabetic retinopathy, an eye disease caused by damage to blood vessels in the retina