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Edwin Lee Christopher Walker Bahram Ayadi Context: Moderate to severe interstitial cystitis (also known as bladder pain syndrome) is a disabling disease with no effective treatment

When PGH synthase is activated, the peroxidase function of the enzyme generates oxygen radicals that could interact with polyunsaturated fatty acids in the placenta to form lipid peroxides

Given the limited safety information available on 5-amino-1MQ, researchers must consider excluding certain groups from their trials until we have more pre-clinical and clinical data

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