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Psychiatry 70 , 16621666 (2009)

RESEARCH USE ONLY These compounds are NOT intended for human consumption, clinical use, or veterinary applications

Importantly, the largest reductions in BMI were observed in the southern United States, which also reported the highest rates of GLP-1 RA dispensing claims (Rader et al., 2024), a geographic concordance that is consistent with a causal contribution of these pharmacotherapies to the observed population-level BMI decline

Digging into the research, you'll find that somewhere between 20% and 50% of people of Chinese, Japanese, and Korean descent have this less-effective ALDH2 enzyme, making them way more likely to experience the flush