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513,514 These signaling pathways suggest that GLP-1 and its receptor agonists may influence the progression of NASH through multiple mechanisms, providing several potential therapeutic targets including: FOXO1, a transcription factor that plays a critical role in regulating glucose and lipid metabolism

Glutamine and transforming growth factor-alpha stimulate extracellular regulated kinases and enhance recovery of villous surface area in porcine ischemic-injured intestine

p62-Nrf2-p62 mitophagy regulatory loop as a target for preventive therapy of neurodegenerative diseases

In prostate cancer, expression of androgen receptormediated LAT3 ( SLC43A1 ) and leucine uptake can be inhibited by anti-androgen treatment, inducing the compensatory upregulation of LAT1 ( SLC7A5 ) (Wang et al., 2011)