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In the STEP 1 trial extension phase, participants who discontinued semaglutide regained approximately two-thirds of their lost weight within one year

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This pressure has led to prescribing decisions that may not fully account for individual risk factors, including susceptibility to pancreatic inflammation and gastrointestinal complications

doi: 10.1016/j.metabol.2018.11.014 6 BifariFManfriniRDei CasMBerraCSianoMZuinMet al