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That said, here are some groups of people who are typically not candidates for semaglutide or advised to use it with caution: History of Pancreatitis Individuals with a history of pancreatitis, which is inflammation of the pancreas, should avoid semaglutide due to the potential risk of exacerbating the condition

Education is also crucial

Nutritional Priorities to support GLP-1 therapy for obesity: a joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medecine Association, and The Obesity Society

Imaging studies (X-ray, MRI, ultrasound) documenting initial status for comparison