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doi: 10.1080/00207454.2021.1924707 [DOI] [PubMed] [Google Scholar] 108

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Notably, these affinity-enhancing mutations reduced the thermal stability of the Fc alone (T M = 50.6 0.1 C, triplicates from N of 2), but the disulfide-linked complex remained stable, with a T M of 70.1 C ( 0.2 C, triplicates from N of 2) (Supplementary Fig

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