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Hydration status significantly affects periorbital appearance with dehydration exaggerating dark circles through increased blood viscosity pooling more visibly, skin dullness from reduced cellular hydration making circles more prominent, and impaired lymphatic function allowing fluid retention despite overall dehydration
Yamamoto, S., Wakimoto, H., Aoyagi, M., Hirakawa, K
(2006) demostr una aceleracin significativa de la formacin del callo seo en la rata, con una mineralizacin ms rpida y una resistencia mecnica mejorada
its effects are secondary to gene expression changes
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