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While research is still ongoing, they have become increasingly popular among active adults, fitness enthusiasts, and individuals recovering from orthopedic injuries because of their potential to promote tissue healing

Damage to the tubular endothelial cells can increase leukocyte adhesion, platelet aggregation, and vasoconstriction, reduce blood flow to nephrons, and damage the glomerular barrier and the extensive network of peritubular capillaries (88)

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