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M cells also contribute to the high concentrations of AMPs present in the intestinal mucosa and additionally produce IgA (Allaire et al

The sequence was Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (in case youre intrigued by the chemistry!) Across the next three decades, the same group and a handful of collaborators published several hundred preclinical studies showing the peptide healed wounds, repaired tendons, attenuated NSAID toxicity, fixed gut lesions, and reduced symptoms in animal models of depression, schizophrenia, and Parkinsons disease

10.1016/j.biopha.2020.110241 51 HecquetC

Guilherme Rizzoto, Ghent University, Belgium