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The Annexin V-Alexa Fluor 488/propidium iodide (PI) dead cell apoptosis kit (Thermo Fisher Scientific V13241) was used to detect early and late apoptosis and necrosis as previously described [18]

3 Results 3.1 Characterization of SBA-15 and SNCDs nanoparticles Functionalized SBA-15 mesoporous silica nanoparticles (MSN) were prepared using an aqueous system that consisted of tetraethyl orthosilicate (TEOS) as the silica precursor and cetyltrimethylammonium bromide (CTAB) as the surfactant, following the methodology described in reference [21]

[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease

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