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In the University of Palermo study, 33% of participants experienced morning nausea and occasional vomiting, though no one discontinued treatment due to these side effects

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Prespecified PMDA bioequivalence criteria were also met, with 90% CIs for the estimated treatment ratios of AUC 024h,SS and C max, 024h,SS within the standard acceptance limits (0.80001.2500)

In animal studies, exenatide increases expression of genes known to be critical for cell function, and enhances cell mass by stimulating cell proliferation and/or neogenesis and also by suppressing apoptosis [37-39]