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In the above animal model, cotadutide administration was associated with reduction of hepatic inflammation and fibrosis, as indicated by decreases in quantitative measures of liver fibrosis, circulating collagen markers, and inflammatory/pro-fibrotic genes [39]
Research has explored its potential interactions with cortisol and luteinizing hormone (LH) secretion, as well as its activity on opioid receptor pathways and antioxidant mechanisms at the cellular level, making it a versatile subject across neuroscience, endocrinology, and oxidative stress research models
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