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M., Zhu, J

Particularly insightful mechanistic evidence comes from a medaka fish NAFLD model, where metabolomic analysis revealed that L-carnitine not only reduced hepatic lipid deposition but also significantly elevated hepatic -oxidation end products (acetyl-CoA and ATP) while upregulating antioxidant enzyme superoxide dismutase 2 (SOD2) (35)

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This convergence of epidemiologic and laboratory data from experimental models of PD lends credence to a causative role of certain pesticides in the neurodegenerative process