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The authors of these studies found Arg35 was highly conserved and was found in 68% of Alpha, Mu, Pi and Sigma GST sequences also containing a catalytic Tyr residue using a query motif [Y] 7X [E, Q, H] 2X [R] 1011X [E, D] 12X [R, K]

The results from these recently completed trials support the findings of the HIV study, said Sekhar, who is currently the Principal Investigator of two NIH-funded randomized clinical trials studying the effect of GlyNAC in older humans with mild cognitive impairment, and with Alzheimers disease