Despite its importance, few is known about actors involved in human gut barrier function, since most of the data are limited to animal studies which have shown that microbiota changes can promote disruption of intestinal barrier homeostasis [37]
Previously, we developed a twelvemonth randomized doubleblind controlled clinical trial in 50 patients with relapsingremitting MS
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On day 4 or 6, macrophages were polarized with or without 100 ng ml 1 lipopolysaccharide (LPS) (Sigma) and 2050 ng ml 1 IFN (PeproTech) for 12 days
