Loose, less cellular areas (Antoni B, figure 2) are composed of a loose oedematous and mucinous stroma with fibrillar collagen
Nicknamed Natures Ozempic, the medicinal plant Berberine helps to improve insulin sensitivity, enhance fat burning and modulate gut microbiota for better metabolic efficiency and cholesterol balance
Interestingly, the same study found that, in rats, tirzepatide suppressed lipid intake without affecting sucrose (carbohydrate) consumption in a choice-based assay, implying that the effects of these medications may be macronutrient specific (Geisler et al., 2023)
Presently, immunomodulatory actions are believed to play a central role in the renoprotective effects of GLP-1 RAs [3, 26,27,28]