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Common gastrointestinal side effects: The most frequently reported adverse effects are gastrointestinal in nature, occurring in up to 40-80% of patients with higher doses, particularly during dose escalation: [13] [14] Nausea (most common, typically improves after 4-8 weeks) Vomiting Diarrhoea or constipation Abdominal discomfort or bloating Reduced appetite These effects can be minimised by starting with low doses and gradually titrating upwards according to manufacturer guidance

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This method protects the surrounding tissue and significantly reduces the risk of lumps or uneven degradation

By applying the patch to the skin, manufacturers claim that the medication can be absorbed slowly into the bloodstream, providing appetite-suppressing effects throughout the day