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In treatment development, repurposing drugs already approved for other conditions has the advantage of providing data and experience from previous research and practical use, Rebecca M

Finally, while the B-vitamins in this formula (riboflavin and niacinamide) are provided in moderate, targeted doses to support the ALDH and MAO pathways, individuals with extreme sensitivities to methylation support should monitor their symptoms

Indications: Overactive bladder Common symptoms include urgency, urinary incontinence, and increased urinary frequency Side Effects: dry mouth constipation headache urinary tract infection angioedema CNS side effects (confusion, hallucinations, sedation) aggravation of decreased GI motility in patients with GI obstructive disorders Pharmacokinetics: taken orally by extended release tablet, 7.5 or 15 mg once daily metabolized by CYP3A4 & CYP2D6 half life 13-19 hrs Notes: the estimated Walmart cost for generic darifenacin is ~$71 for a supply of 30 generic 15 mg tablets (GoodRx.com

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