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Thus, alternative targeting approaches that are tailored to inherent biological differences should lead to better therapeutics

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In a diabetic kidney disease model, it was observed that the renal tissue shows a significant increase in iron ion content, elevated levels of MDA and 4-hydroxynonenal (4-HNE), decreased GSH, markedly decreased FTH1 expression, significantly increased TFR-1 expression

(2019) investigated the differences in metabolic flux pathways and ketogenesis at the basal level of C8:0 and C10:0 using human-induced pluripotent stem cell-derived (iPSC) astrocytes