semaglutide backorder Makers of compounded Wegovy, Ozempic threatened by FDA move The Ozempic Shortage Is Over

Taouzinet L, Fatmi S, Lahiani-Skiba M, Skiba M, Iguer-Ouada M

The plaintiffs must share common legal questions or facts that apply across the entire group

Tirzepatide activates both GLP-1 and GIP (glucose-dependent insulinotropic peptide) receptors, producing greater weight loss than semaglutide alone in head-to-head trials

Because Wegovy (when approved at its highest dose) produces rapid weight loss and sharper metabolic shifts, this could drive the stronger association by predisposing to optic nerve hypoperfusion through intravascular volume contraction, hypotension with nocturnal dips and autonomic instability. For ophthalmologists, the findings highlight a potential safety signal that warrants further investigation but should be interpreted cautiously