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2018, In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats, Archives of Toxicology 92:32073221

According to a Clinicians Guide in a University of Virginia report published in 2018, the condition may not fully resolve for up to eight weeks, however (8) Neurologic symptoms, like tingling, numbness in hands and feet, or dizziness, generally improve in six to 12 weeks, and severe neurological symptoms, like difficulty walking, may not ever resolve completely

Current research gaps include limited understanding of derivatives long-term safety profiles and metabolic fate