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Available from: Accessed 28 June 2025 van Zuylen ML, Siegelaar SE, Plummer MP, et al

A Phase IIb trial of mRNA-4157 in combination with pembrolizumab for patients with resected high-risk melanoma showed that this combination therapy prolonged recurrence-free survival compared with pembrolizumab monotherapy and had a manageable safety profile

It communicates with retinoid receptors that all of us have on our skin to encourage cell turnover and help boost skins natural production of collagen and elastin two key components in keeping skin looking and feeling younger (1, 2, 3)