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How different concentrations affect your dosing protocol Choosing between concentrations is not just a convenience decision

In a 48-week, placebo-controlled phase-2 trial (338 participants) reported by Lilly, the highest dose achieved a mean weight reduction of 24.2% (about 57.8 lb) at the end of treatment

A transport protein is needed to take up carnitine against this gradient and this transport is the limiting factor

Structure MOL SDF PDB SMILES InChI View Structure Structure for L-carnitine (PAMDB110763) Synonyms: -trimethyl-hydroxybutyrobetaine 3-hydroxy-4-trimethylammoniobutanoate R-(-)-3-hydroxy-4-trimethylaminobutyrate vitamin B T bicarnesine ( R )-carnitine -L-trimethyl--hydroxybutyrobetaine vitamin Bt 3-carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium Chemical Formula: C 7 H 15 NO 3 Average Molecular Weight: 161.2 Monoisotopic Molecular Weight: 162.1130183851 InChI Key: PHIQHXFUZVPYII-ZCFIWIBFSA-N InChI: InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1 CAS number: Not Available IUPAC Name: (3 R )-3-hydroxy-4-(trimethylammonio)butanoate Traditional IUPAC Name: Not Available SMILES: C(C(O)CC(=O)[O-])[N+](C)(C)C Chemical Taxonomy Taxonomy Description This compound belongs to the class of organic compounds known as carnitines