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Deposition or iron may occur following excess dietary intake or treatment by xenobiotics (Popp and Cattley 1991;Greaves 2007

The limited in vitro lifetime of human diploid cell strains

The framing throughout reflects the compound's actual status as a research peptide of substantial laboratory interest with a well-characterized coordination chemistry, well-grounded connections to copper-dependent extracellular matrix biology, and a distinctive cosmetic-ingredient regulated use that operates under different evidentiary frameworks from pharmaceutical approval

In other words, it is not a synthetic invention so much as a naturally occurring signaling molecule that researchers have tried to understand and, in places, to study therapeutically