flow trial semaglutide renal outcomes 2024 FLOWing with the — NephJC Chronic Kidney Disease | Ozempic®

Weight loss injections may carry potential side effects, including nausea, dizziness, headaches, or injection site reactions

Potential Impact on IGF-1 Levels Sermorelin peptides can indirectly influence insulin-like growth factor 1 (IGF-1), a hormone important for growth and development

It's important to note that the SURMOUNT-1 trial shows that when dosing tirzepatide for weight loss, doses of 10mg/weekly and 15mg/weekly lead to an almost identical reduction of body weight

Co-administration leads to greater reductions in albuminuria and more pronounced initial declines in eGFR, indicative of reduced intraglomerular pressure [122,123]