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Secondary outcomes Five included studies comprising 3605 patients reported change in MCV, four studies comprising 140 patients reported change in homocysteine levels, four studies comprising 3588 patients reported change in platelets count, and only three studies with 3430 patients reported change in WBC count

These can include: Persistent nausea and vomiting Severe diarrhea or constipation Abdominal pain and bloating Acid reflux For some, these symptoms are not mild and can significantly impact their quality of life, leading them to discontinue the medication

Not directly cited, making any specific mention of HIFU